PCK2 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 14892-1-AP

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Freight/Packing

Con: 25 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human brain tissue, human colon tissue, rat brain tissue

Positive IHC detected in:
human breast cancer tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
phosphoenolpyruvate carboxykinase 2 (mitochondrial)

Calculated molecular weight:
71 kDa

Observed molecular weight:
71 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PCK2

Synonyms
PCK2, PEPCK, PEPCK M, PEPCK2
Background

PCK2(phosphoenolpyruvate carboxykinase [GTP], mitochondrial) is also named as PEPCK2, PEPCK-M and belongs to the phosphoenolpyruvate carboxykinase [GTP] family. It catalyses the irreversible conversion of oxaloacetate to phosphoenolpyruvate, an important initial step in hepatic gluconeogenesis.Defects in PCK2 are the cause of mitochondrial phosphoenolpyruvate carboxykinase deficiency (M-PEPCKD). It has 2 isoforms produced by alternative splicing with the molecular weight of 71 kDa and 48 kDa.


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