AMPK alpha 1 Antibody 15 Publications

Rabbit Polyclonal| Catalog number: 10929-2-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 56 μg/150 μl

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Species specificity:
human, mouse, rat, zebrafish

Positive WB detected in:
HeLa cells, rat heart tissue

Positive IHC detected in:
human prostate cancer tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:200-1:1000
IHC : 1:100-1:400
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
protein kinase, AMP-activated, alpha 1 catalytic subunit

Calculated molecular weight:
63 kDa

Observed molecular weight:
64 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PRKAA1

Synonyms
AMPK, AMPK alpha, AMPK alpha 1, AMPK subunit alpha 1, AMPK1, AMPKa1, PRKAA1
Background

The mammalian 5-prime-AMP-activated protein kinase (AMPK) appears to play a role in protecting cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. PRKAA1 is also named as AMPK1, ACACA kinase, HMGCR kinase. It is a mammalian homologue of sucrose non-fermenting protein kinase (SNF-1), which belongs to a serine/threonine protein kinase family. It has 2 isoforms with molecular mass of 63-66 kDa produced by alternative splicing.


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