HOP2 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 11339-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 20 μg/150 μl

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Species specificity:
human

Positive WB detected in:
K-562 cells, Jurkat cells

Positive IP detected in:
Jurkat cells

Positive IHC detected in:
human lung cancer tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
PSMC3 interacting protein

Calculated molecular weight:
25 kDa

Observed molecular weight:
24 kDa and 29 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PSMC3IP

Synonyms
GT198, HOP2, HUMGT198A, PSMC3 interacting protein, PSMC3IP, TBP 1 interacting protein, TBPIP
Background

PSMC3IP, also called HOP2, encodes a protein that functions in meiotic recombination. It is a subunit of the PSMC3IP/MND1 complex, which interacts with PSMC3/TBP1 to stimulate DMC1- and RAD51-mediated strand exchange during meiosis. The protein encoded by this gene can also co-activate ligand-driven transcription mediated by estrogen, androgen, glucocorticoid, progesterone, and thyroid nuclear receptors. Mutations in this gene cause XX female gonadal dysgenesis.


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