Pericentrin Polyclonal antibody

Pericentrin Polyclonal Antibody for IF,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, Canine

Applications

IF,ELISA

Conjugate

Unconjugated

Cat no : 22271-1-AP

Synonyms

KEN, Kendrin, KIAA0402, MOPD2, PCN, PCNT, PCNT2, PCNTB, PCTN2, pericentrin, Pericentrin B, SCKL4



Tested Applications

Positive IF detected inMDCK cells

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Published Applications

IFSee 1 publications below

Product Information

22271-1-AP targets Pericentrin in IF,ELISA applications and shows reactivity with human, Canine samples.

Tested Reactivity human, Canine
Cited Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name pericentrin
Calculated molecular weight 378 kDa
GenBank accession numberNM_006031
Gene symbol PCNT
Gene ID (NCBI) 5116
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

PCNT, also named as KIAA0402, PCNT2, Pericentrin-B and Kendrin, is an integral component of the filamentous matrix of the centrosome involved in the initial establishment of organized microtubule arrays in both mitosis and meiosis. PCNT plays a role, together with DISC1, in the microtubule network formation. Is an integral component of the pericentriolar material (PCM). PCNT is a marker of centrosome. Defects in PCNT are the cause of microcephalic osteodysplastic primordial dwarfism type 2 (MOPD2). The antibody is specific to PCNT, and it can recognize isoform 1 and 2.

Protocols

Product Specific Protocols
IF protocol for Pericentrin antibody 22271-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanIF

Elife

De novo centriole formation in human cells is error-prone and does not require SAS-6 self-assembly.

Authors - Won-Jing Wang