RAD51 Antibody 6 Publications

Rabbit Polyclonal| Catalog number: 14961-1-AP

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Freight/Packing

Con: 34 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
mouse testis tissue, HeLa cells

Positive IP detected in:
mouse testis tissue

Positive IHC detected in:
human testis tissue

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)

Calculated molecular weight:
37 kDa

Observed molecular weight:
37 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
RAD51

Synonyms
BRCC5, HRAD51, HsRad51, HsT16930, RAD51, RAD51 homolog A, RAD51A, RECA
Background

RAD51 plays a critical role in the maintenance of genomic integrity by functioning in the repair of DNA double-strand breaks. It mediates homologous pairing and strand exchange in recombinatory structures known as RAD51foci in the nucleus. It also can bind to single and double stranded DNA and exhibits DNA-dependent ATPase activity. In addition, it has a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.


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