RPE65 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 17939-1-AP

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Freight/Packing

Con: 28 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
Y79 cells, HeLa cells, mouse eye tissue, PC-3 cells

Recommended dilution:
WB : 1:500-1:3000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
retinal pigment epithelium-specific protein 65kDa

Calculated molecular weight:
533aa,61 kDa

Observed molecular weight:
65kd,61kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
RPE65

Synonyms
LCA2, mRPE65, rd12, Retinoid isomerohydrolase, Retinol isomerase, RP20, RPE65, sRPE65
Background

RPE65(Retinal pigment epithelium-specific 65 kDa protein) is also named as retinoid isomerohydrolase with the calculated molecular weight og 61 kDa and belongs to the carotenoid oxygenase family. It is a microsomal protein with isomerase activity in the retinoid visual cycle that playing a role in the isomerisation of all-trans (vitamin A) to 11-cis retinal, the chromophore of the visual pigments. It also might be involved in retinoid uptake of keratinocytes.


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