SMN (Human-Specific) Antibody 0 Publications

Mouse Monoclonal| Catalog number: 60154-1-Ig |CloneNo.: 2C6D9

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Con: 150 μg/150 μl

Choose size:

Please visit your regions distributor:

Species specificity:

Positive WB detected in:
A375 cells, HepG2 cells, Raji cells

Positive IP detected in:
HEK-293 cells

Positive IHC detected in:
human brain tissue, human heart tissue, human kidney tissue, human liver tissue

Positive IF detected in:
HepG2 cells

Positive FC detected in:
Jurkat cells,

Recommended dilution:
WB : 1:1000-1:6000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Purification method:
Protein A purification


PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Full name:
survival of motor neuron 2, centromeric

Calculated molecular weight:
282aa,30 kDa

Observed molecular weight:
38 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol

C BCD541, Component of gems 1, Gemin 1, SMN, SMN1, SMN1,SMN, SMN2, SMNC, SMNT, Survival motor neuron protein

The survival of motor neurons (SMN) genes are the disease genes of spinal muscular atrophy (SMA), a common motor neuron degenerative disease. The level of SMN protein correlates with phenotypic severity of SMA. SMA patients lack a functional SMN1 gene, but they possess an intact SMN2 gene, which though nearly identical to SMN1, is only partially functional, because a large majority of SMN2 transcripts lack exon 7, resulting in production of a truncated, less stable SMN protein. This antibody 60154-1-Ig is specific to human SMN2. It can't recognize mouse and rat SMN.

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