|Positive WB detected in||human testis tissue, DU 145 cells|
|Western Blot (WB)||WB : 1:500-1:1000|
|Sample-dependent, check data in validation data gallery|
55170-1-AP targets TAF1L in WB, IHC,ELISA applications and shows reactivity with human, mouse samples.
|Tested Reactivity||human, mouse|
|Host / Isotype||Rabbit / IgG|
|Full Name||TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like|
|Calculated molecular weight||207 kDa|
|Observed molecular weight||250-260 kDa|
|GenBank accession number||NM_153809|
|Gene ID (NCBI)||138474|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Aliquoting is unnecessary for -20oC storage.|
TAF1L, also named as TAF(II)210, belongs to the TAF1 family. It may act as a functional substitute for TAF1/TAFII250 during male meiosis, when sex chromosomes are transcriptionally silenced. The antibody is specific to TAF1L.
Overexpression of TAF1L Promotes Cell Proliferation, Migration and Invasion in Esophageal Squamous Cell Carcinoma.
Int J Biol Sci
TAF1L promotes development of oral squamous cell carcinoma via decreasing autophagy-dependent apoptosis.