TFAM Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 22586-1-AP

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Freight/Packing

Con: 42 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
MCF7 cells,K-562 cells, HeLa cells, human testis tissue, HEK-293 cells, A431 cells, Jurkat cells, HepG2 cells

Positive IP detected in:
HEK-293 cells

Positive IHC detected in:
human kidney tissue, human kidney tissue, human testis tissue

Recommended dilution:
WB : 1:500-1:3000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
transcription factor A, mitochondrial

Calculated molecular weight:
246aa,29 kDa

Observed molecular weight:
25 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
TFAM

Synonyms
MtTF1, mtTFA, TCF 6, TCF6, TCF6L1, TCF6L2, TCF6L3, TFAM, Transcription factor 6, Transcription factor 6 like 2
Background

TFAM, also named as TCF6L2, MtTF1, TCF6, TCF6L1, TCF6L3 and mtTFA, is a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. It is involved in mitochondrial transcription regulation. TFAM is required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. It activates transcription by binding immediately upstream of transcriptional start sites. TFAM is able to unwind and bend DNA.


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