TNNC1 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 13504-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 86 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
mouse skeletal muscle tissue, human stomach tissue

Positive IP detected in:
mouse heart tissue

Positive IHC detected in:
human skeletal muscle tissue, human heart tissue, human lung tissue, human skeletal muscle tissue

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
troponin C type 1 (slow)

Calculated molecular weight:
161aa,18 kDa

Observed molecular weight:
18 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
TNNC1

Synonyms
CMD1Z, TN C, TNC, TNNC, TNNC1, troponin C type 1 (slow)
Background

Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. TnC plays an important role in excitation-contraction coupling and is the primary target of compounds such as levosimendan that augment Ca2+ responsiveness of the thin filament.


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