TRPA1 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 19124-1-AP

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Freight/Packing

Con: 51 μg/150 μl

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Species specificity:
human

Positive WB detected in:
SH-SY5Y cells

Positive FC detected in:
SH-SY5Y cells

Recommended dilution:
WB : 1:500-1:2000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
transient receptor potential cation channel, subfamily A, member 1

Calculated molecular weight:
140 kDa

Observed molecular weight:
120-130 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
TRPA1

Synonyms
ANKTM1, TRPA1
Background

TRPA1, also named as ANKTM1, belongs to the transient receptor family. TRPA1 is a receptor-activated non-selective cation channel involved in detection of pain and possibly also in cold perception and inner ear function. TRPA1 has a central role in the pain response to endogenous inflammatory mediators and to a diverse array of volatile irritants, such as mustard oil, garlic and acrolein, an irritant from tears gas and vehicule exhaust fumes. It acts also as a ionotropic cannabinoid receptor by being activated by delta(9)-tetrahydrocannabinol (THC), the psychoactive component of marijuana. It may be a component for the mechanosensitive transduction channel of hair cells in inner ear, thereby participating in the perception of sounds.


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