YWHAZ Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 14881-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 22 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
Raji cells,mouse brain tissue, Jurkat cells

Recommended dilution:
WB : 1:500-1:2000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide

Calculated molecular weight:
28 kDa

Observed molecular weight:
28-30 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
YWHAZ

Synonyms
14 3 3 protein zeta/delta, 14-3-3, KCIP 1, YWHAZ
Background

YWHAZ (also known as 14-3-3 zeta) is a member of 14-3-3 proteins which were the first phosphoserine/phosphothreonine-binding proteins to be discovered. 14-3-3 family members interact with a wide spectrum of proteins and possess diverse functions. Mammals express seven distinct 14-3-3 isoforms (gamma, epsilon, beta, zeta, sigma, theta, tau) that form multiple homo- and hetero- dimmers. 14-3-3 proteins display the highest expression levels in the brain, and have been implicated in several neurodegenerative diseases, including Alzheimer's disease and amyotrophic lateral sclerosis. This antibody was raised against the full-length YWHAZ.


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