CISD1 Antibody 12 Publications

Rabbit Polyclonal| Catalog number: 16006-1-AP

  • Print page
  • Download PDF

Be the first to review this product


-_-

Freight/Packing

Con: 35 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human, mouse, zebrafish, rat

Positive WB detected in:
mouse skeletal muscle tissue,mouse heart tissue, HepG2 cells, human skeletal muscle tissue

Positive IP detected in:
HepG2 cells

Positive IHC detected in:
human heart tissue,human spleen tissue, human kidney tissue, human testis tissue, human placenta tissue, human brain tissue, human ovary tissue, human liver tissue

Positive IF detected in:
Hela cells

Positive FC detected in:
HeLa cells

Recommended dilution:
WB : 1:1000-1:4000
IP : 0.5-4.0 ug for IP and 1:1000-1:4000 for WB
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
CDGSH iron sulfur domain 1

Calculated molecular weight:
108aa,12 kDa

Observed molecular weight:
14-17 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CISD1

Synonyms
C10orf70, CDGSH iron sulfur domain 1, CISD1, MDS029, mitoNEET, Mnt, ZCD1
Background

MitoNEET, also named CISD1, belongs to a previously uncharacterized ancient family of proteins for which the hallmark is the presence of a unique 39 amino acid CDGSH domain. It is a single-pass type III membrane protein, located in mitochondrion outer membrane and may play a role in regulating maximal capacity for electron transport and oxidative phosphorylation. MitoNEET is a recently identified drug target for a commonly prescribed diabetes drug, Pioglitazone. This antibody recognizing MitoNEET (calculated 12 kDa) as a 17 kDa protein may be due to its posttranslational modification or metal binding activity.


Back
to top