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Product Information
83090-1-RR targets PLCZ1 in ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | PLCZ1 fusion protein Ag26899 Predict reactive species |
| Full Name | phospholipase C, zeta 1 |
| Calculated Molecular Weight | 608 aa, 70 kDa |
| GenBank Accession Number | BC125067 |
| Gene Symbol | PLCZ1 |
| Gene ID (NCBI) | 89869 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q86YW0 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
Phospholipase C zeta1 (Plcz1) was known to be a physiological factor in sperm that activates oocytes to complete meiosis by triggering Ca2+ oscillations after fertilisation (PMID: 36613757). PLCZ1 is considered a major sperm-borne oocyte activation factor. After gamete fusion, PLCZ1 triggers calcium oscillations in the oocyte, resulting in oocyte activation (PMID: 38133249).
