Recombinant Human Resistin protein (rFc Tag)
Species
Human
Purity
>90 %, SDS-PAGE
Tag
rFc Tag
Activity
not tested
Cat no : Eg5393
Validation Data Gallery
Product Information
| Purity | >90 %, SDS-PAGE |
| Endotoxin | <0.1 EU/μg protein, LAL method |
| Activity |
Not tested |
| Expression | HEK293-derived Human Resistin protein Lys19-Pro108 (Accession# Q9HD89) with a rabbit IgG Fc tag at the N-terminus. |
| GeneID | 56729 |
| Accession | Q9HD89 |
| PredictedSize | 36.4 kDa |
| SDS-PAGE | 35-43 kDa, reducing (R) conditions |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| Reconstitution | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| Storage Conditions |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Background
Resistin is a member of the resistin-like molecule family (RELMs) that includes three additional proteins, RELM-α, RELM-β, RELM-y . Resistin is almost exclusively expressed in white adipocytes in mice, whereas macrophages are the primary source in humans . In a variety of pathophysiologic states, particularly in type 2 diabetes mellitus and in chronic kidney disease, the serum concentration of resistin is increased.
References:
1. Cohen, Gerald, and Walter H Hörl. Seminars in dialysis vol. 22,4 (2009): 373-7. 2. Sudan, Sarabjeet Kour et al. Biochimica et biophysica acta. Reviews on cancer vol. 1874,2 (2020): 188419.