Product Information
14083-1-AP targets ADAM22 in ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | ADAM22 fusion protein Ag5211 Predict reactive species |
| Full Name | ADAM metallopeptidase domain 22 |
| Calculated Molecular Weight | 342 aa, 40 kDa |
| GenBank Accession Number | BC036029 |
| Gene Symbol | ADAM22 |
| Gene ID (NCBI) | 53616 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9P0K1 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
ADAM22 is a transmembrane protein with an extracellular disintegrin and catalytically inactive metalloproteinase domain that is thought to participate in cell-cell and cell-matrix interactions. It is a component of the Kv1 channel protein complex. ADAM22 is previously reported to regulate synaptic transmission and to be a binding partner of leucine-rich glioma inactivated 1 (Lgi1), which is mutated in autosomal-dominant partial epilepsy with auditory features(PMID: 20089912). It has 5 isoforms produced by alternative splicing. This protein has a signal peptide, a propeptide and 4 glycosylation sites.
