AFP Antibody 16 Publications

Rabbit Polyclonal| Catalog number: 14550-1-AP

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Freight/Packing

Con: 62 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human brain tissue, BxPC-3 cells, HepG2 cells, human heart tissue, rat brain tissue, SH-SY5Y cells, SW 1990 cells

Positive IP detected in:
HepG2 cells

Positive IHC detected in:
human liver cancer tissue, human liver cancer tissue, human ovary tumor tissue

Recommended dilution:
WB : 1:1000-1:4000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
alpha-fetoprotein

Calculated molecular weight:
69 kDa

Observed molecular weight:
68-72 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
AFP

Synonyms
AFP, Alpha 1 fetoprotein, Alpha fetoglobulin, alpha fetoprotein, FETA, HPAFP
Background

AFP, also known as Alpha-fetoprotein, is a major plasma protein in the fetus and its concentration is very low in the adult. So AFP is usually considered a marker of hepatocyte precursors. AFP can be detected at abnormally high concentrations in hepatocellular carcinomas as well as in the plasma and ascitic fluid of adults with hepatoma. High AFP concentrations have been correlated with tumor cell growth, indicating that AFP can serve as a tumor marker.


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