ALDH1A2 Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 13951-1-AP

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Freight/Packing

Con: 53 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse testis tissue, K-562 cells

Positive IP detected in:
mouse testis tissue

Positive IHC detected in:
human testis tissue

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
aldehyde dehydrogenase 1 family, member A2

Calculated molecular weight:
518aa,57 kDa

Observed molecular weight:
53-57 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ALDH1A2

Synonyms
ALDH1A2, RALDH 2, RALDH(II), RALDH2, RALDH2 T, Retinal dehydrogenase 2
Background

ALDH1A2(aldehyde dehydrogenase family 1 member A2) is also named as RALDH2(retinal dehydrogenase 2) and belongs to the aldehyde dehydrogenase family. It is a cytosolic homotetramer(56.7 kDa subunits) exhibiting complex expression patterns throughout embryonic development. ALDH1A2 plays a role in retinoid metabolism during embryonic development where it is considered to be the major retinoic acid-synthesizing enzyme during early embryogenesis(PMID:20735668). Its expression is reduced in primary prostate tumors compared with normal prostate tissue suggested that it is normally expressed in the epithelial compartment of prostate tissue(PMID:16166285).It has 2 isoforms produced by alternative splicing.


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