APBB3 Polyclonal antibody

APBB3 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (1)

Applications

WB, ELISA

Conjugate

Unconjugated

Publications

1

Cat no : 12051-1-AP

Synonyms

APBB3, FE65L2, Protein Fe65 like 2, SRA

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Validation Data Gallery

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  WB analysis of human plasma using 12051-1-AP

  human plasma were subjected to SDS PAGE followed by western blot with 12051-1-AP (APBB3 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

• 

  WB analysis using 12051-1-AP

  human plasma were subjected to SDS PAGE followed by western blot with 12051-1-AP (APBB3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: human plasma

Recommended dilution

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Published Applications

• WB: See 1 publications below

Product Information

12051-1-AP targets APBB3 in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Cited Reactivity: mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: APBB3 fusion protein Ag2681
• Full Name: amyloid beta (A4) precursor protein-binding, family B, member 3
• Calculated Molecular Weight: 486 aa, 53 kDa
• Observed Molecular Weight: 53 kDa
• GenBank Accession Number: BC013158
• Gene Symbol: APBB3
• Gene ID (NCBI): 10307
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

APBB3 is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP.

Publications

Species	Application	Title
mouse	WB	J Nanobiotechnology; Pro-efferocytic macrophage membrane biomimetic nanoparticles for the synergistic treatment of atherosclerosis via competition effect; Authors - Xuan Sha