Tested Applications
| Positive WB detected in | human plasma |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
12051-1-AP targets APBB3 in WB, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Cited Reactivity | mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag2681 Product name: Recombinant human APBB3 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 187-486 aa of BC013158 Sequence: HSLIHCQPLVHIRVWGVGSSKGRDRDFAFVASDKDSCMLKCHVFRCDVPAKAIASALHGLCAQILSERVEVSGDASCCSPDPISPEDLPRQVELLDAVSQAAQKYEALYMGTLPVTKAMGMDVLNEAIGTLTARGDRNAWVPTMLSVSDSLMTAHPIQAEASTEEEPLWQCPVRLVTFIGVGRDPHTFGLIADLGRQSFQCAAFWCQPHAGGLSEAVQAACMVQYQKCLVASAARGKAWGAQARARLRLKRTSSMDSPGGPLPLPLLKGGVGGAGATPRKRGVFSLLDAFRLKPSLLHMP Predict reactive species |
| Full Name | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| Calculated Molecular Weight | 486 aa, 53 kDa |
| Observed Molecular Weight | 53 kDa |
| GenBank Accession Number | BC013158 |
| Gene Symbol | APBB3 |
| Gene ID (NCBI) | 10307 |
| RRID | AB_3085387 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | O95704 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
APBB3 is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for APBB3 antibody 12051-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
What published studies show
The APBB3 Polyclonal antibody (Cat# 12051-1-AP) has 1 citation. It was cited in J Nanobiotechnology (Impact Factor: 15), in a study on pro-efferocytic macrophage membrane biomimetic nanoparticles for synergistic atherosclerosis treatment via competition effect. The research field encompasses nanobiotechnology, macrophage biology, and cardiovascular disease therapeutics. The antibody was applied in Western Blot (WB) with mouse species.
| Species | Application | Title |
|---|---|---|
J Nanobiotechnology Pro-efferocytic macrophage membrane biomimetic nanoparticles for the synergistic treatment of atherosclerosis via competition effect |



