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ARG2 Polyclonal antibody

ARG2 Polyclonal Antibody for IHC, WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IF,ELISA

Conjugate

Unconjugated

Cat no : 14825-1-AP

Synonyms

ARG2, Arginase 2, mitochondrial, arginase, type II, Kidney type arginase, Non hepatic arginase, Type II arginase



Tested Applications

Positive WB detected inCaco-2 cells, HEK-293 cells, mouse liver tissue, rat liver tissue
Positive IHC detected inhuman prostate cancer tissue, human kidney tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:4000
Immunohistochemistry (IHC)IHC : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

14825-1-AP targets ARG2 in WB, IHC, IF,ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen ARG2 fusion protein Ag6609
Full Name arginase, type II
Calculated molecular weight 39 kDa
Observed molecular weight 39-42 kDa
GenBank accession numberBC001350
Gene symbol ARG2
Gene ID (NCBI) 384
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

ARG2(Arginase-2, mitochondrial) is also named as kidney-type arginase, non-hepatic arginase and belongs to the arginase family. It may play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis.

Protocols

Product Specific Protocols
WB protocol for ARG2 antibody 14825-1-APDownload protocol
IHC protocol for ARG2 antibody 14825-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseWB,IHC

J Cell Mol Med

PTPN2 improved renal injury and fibrosis by suppressing STAT-induced inflammation in early diabetic nephropathy.

Authors - Ya Li
humanWB

Life Sci

Ornithine is a key mediator in hyperphosphatemia-mediated human umbilical vein endothelial cell apoptosis: Insights gained from metabolomics.

Authors - Rong Zhou
mouseWB

Biochim Biophys Acta

Reduced bioavailable manganese causes striatal urea cycle pathology in Huntington's disease mouse model.

Authors - Terry Jo V Bichell
mouseWB

Biomed Pharmacother

PMID: 30889486

Authors - Lu Gao
mouseWB

J Lipid Res

Macrophage-derived apoESendai suppresses atherosclerosis while causing lipoprotein glomerulopathy in hyperlipidemic mice.

Authors - Hagai Tavori
mouseIF

Circulation

Deletion of Macrophage Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Accelerates Atherosclerosis Regression and Increases C-C Chemokine Receptor Type 7 (CCR7) Expression in Plaque Macrophages.

Authors - Paul A Mueller