• Featured Product
  • KD/KO Validated

ARNTL Polyclonal antibody

ARNTL Polyclonal Antibody for IHC, IP, WB,ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat





Cat no : 14268-1-AP


ARNT3, ARNTL, bHLH PAS protein JAP3, bHLHe5, BMAL1, BMAL1c, Brain and muscle ARNT like 1, JAP3, Member of PAS protein 3, MOP3, PASD3, TIC

Tested Applications

Positive WB detected inHeLa cells, HT-1080 cells, 3T3-L1 cells
Positive IP detected inHeLa cells
Positive IHC detected inhuman prostate cancer tissue, human colon cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

Western Blot (WB)WB : 1:500-1:3000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
Immunohistochemistry (IHC)IHC : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

14268-1-AP targets ARNTL in WB, IP, IHC, chIP,ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen ARNTL fusion protein Ag5586
Full Name aryl hydrocarbon receptor nuclear translocator-like
Calculated molecular weight 69 kDa
Observed molecular weight 69-75 kDa
GenBank accession numberBC041129
Gene symbol ARNTL
Gene ID (NCBI) 406
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

BMAL1, a basic helix-loop-helices with Per-Arnt-Sim (PAS) domain transcription factor, is one of components that has core clock function in mammals. It form a heterodimer with CLOCK, and induce the transcription of target genes by binding to E-box elements within their promoter regions. And this transcription is inhibited in a feedback loop by PER, and also by CRY proteins.Also BMAL1 is a key player in the regulation of metabolism, playing a role in adipogenesis and in the control of glucose and triglycerides levels.


Product Specific Protocols
WB protocol for ARNTL antibody 14268-1-APDownload protocol
IHC protocol for ARNTL antibody 14268-1-APDownload protocol
IP protocol for ARNTL antibody 14268-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



J Exp Clin Cancer Res

PMID: 30621723

Authors - Hao Peng
  • KD Validated

Hum Cell

Pathophysiological significance of clock genes BMAL1 and PER2 as erythropoietin-controlling factors in acute blood hemorrhage.

Authors - Naoto Tani

Cell Death Dis

hPER3 promotes adipogenesis via hHSP90AA1-mediated inhibition of Notch1 pathway.

Authors - Xinxing Wan

J Immunol Res

Suppression of DLBCL Progression by the E3 Ligase Trim35 Is Mediated by CLOCK Degradation and NK Cell Infiltration.

Authors - Xiyan Tan

Mol Cell Neurosci

Downregulation of the spinal dorsal horn clock gene Per1 expression leads to mechanical hypersensitivity via c-jun N-terminal kinase and CCL2 production in mice.

Authors - Norimitsu Morioka

Oncol Rep

Circadian clock protein CRY1 prevents paclitaxel‑induced senescence of bladder cancer cells by promoting p53 degradation.

Authors - Min Jia