Product Information
84863-5-PBS targets ACBP/DBI in WB, Indirect ELISA applications and shows reactivity with mouse, rat samples.
Tested Reactivity | mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | ACBP/DBI fusion protein Eg2462 Predict reactive species |
Full Name | diazepam binding inhibitor |
Calculated Molecular Weight | 10KDa |
Observed Molecular Weight | 10 kDa |
GenBank Accession Number | NM_007830.4 |
Gene Symbol | Dbi |
Gene ID (NCBI) | 13167 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | P31786 |
Storage Buffer | PBS only, pH 7.3. |
Storage Conditions | Store at -80°C. |
Background Information
Acbp/Dbi (acyl-CoA binding protein/Diazepam-binding inhibitor) is a widely expressed protein that binds long-chain fatty acyl-CoA esters and plays a role in fatty acyl-CoA transport and pool formation. Acbp/Dbi is critical to cellular proliferation, differentiation, mitochondrial functions, and autophagy. Deletion of Acbp in mouse results in sebocyte hyperplasia and sparse, matted hair with a greasy appearance (PMID: 32632162, 16902415).