|Positive WB detected in||Jurkat cells, MCF-7 cells|
|Western Blot (WB)||WB : 1:1000-1:4000|
|Sample-dependent, check data in validation data gallery|
The immunogen of 26809-1-AP is BCLAF1 Fusion Protein expressed in E. coli.
|Cited Reactivity||human, pig|
|Host / Isotype||Rabbit / IgG|
|Immunogen||BCLAF1 fusion protein Ag25210|
|Full Name||BCL2-associated transcription factor 1|
|Calculated molecular weight||920 aa, 106 kDa|
|Observed molecular weight||145 kDa|
|GenBank accession number||BC132780|
|Gene ID (NCBI)||9774|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
BCLF1, also named as Bcl-2-associated transcription factor 1, is a 920 amino acid protein, which Interacts with Bcl-2 related proteins, EMD, with the adenovirus E1B 19 kDa protein and with DNA. BCLF1 as a death-promoting transcriptional repressor may be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. The calculated molecular weight of BCLF1 is a 110 kDa, but the modified BCLF1 protein is about 140-150 kDa.
Aging (Albany NY)
LncRNA PVT1 accelerates malignant phenotypes of bladder cancer cells by modulating miR-194-5p/BCLAF1 axis as a ceRNA.
Nucleic Acids Res
The N6-methyladenosine RNA-binding protein YTHDF1 modulates the translation of TRAF6 to mediate the intestinal immune response.