Biglycan Monoclonal antibody, PBS Only

Biglycan Monoclonal Antibody for Indirect ELISA, IHC, WB
Cat No. 67275-1-PBS
Clone No.1E3F2

Host / Isotype

Mouse / IgG2a

Reactivity

pig, mouse, human

Applications

Indirect ELISA, IHC, WB

BGN, 1E3F2, PG-S1, PGI, PG S1

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Product Information

67275-1-PBS targets Biglycan in Indirect ELISA, IHC, WB applications and shows reactivity with pig, mouse, human samples.

Tested Reactivity pig, mouse, human
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen

CatNo: Ag8012

Product name: Recombinant human Biglycan protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 1-368 aa of BC004244

Sequence: MWPLWRLVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVPSGLPDLKLLQVVYLHSNNITKVGVNDFCPMGFGVKRAYYNGISLFNNPVPYWEVQPATFRCVTDRLAIQFGNYKK

Predict reactive species
Full Name biglycan
Calculated Molecular Weight 42 kDa
Observed Molecular Weight 48 kDa
GenBank Accession NumberBC004244
Gene Symbol Biglycan
Gene ID (NCBI) 633
RRIDAB_2882544
Conjugate Unconjugated
FormLiquid
Purification MethodProtein A purification
UNIPROT IDP21810
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

Biglycan is a member of the small leucine-rich proteoglycan (SLRP) family (PMID: 18463092). It consists of a core protein of 42 kDa containing leucine-rich repeats (LRRs), to which two chondroitin/dermatan sulfate side chains are covalently bound (PMID: 2212616; 10383378). The tissue-specific chondroitin- or dermatan-sulfate glycosaminoglycan chains of biglycan are attached to amino acid residues at the N-terminus of the core protein (PMID: 22821552). Biglycan is a ubiquitous component of connective tissue matrix and may act as a signaling molecule (PMID: 22821552). Upregulation of biglycan has been reported in multiple types of solid cancer (PMID: 32194659).

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