C2orf69 Polyclonal antibody, PBS Only

• 

  WB analysis using 32100-1-AP (same clone as 32100-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32100-1-AP (C2orf69 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32100-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse kidney using 32100-1-AP (same clone as 32100-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 32100-1-AP (C2orf69 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 32100-1-PBS in a different storage buffer formulation.

C2orf69 Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 32100-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

mouse, rat

Applications

WB, IHC, Indirect ELISA

Synonyms

Chromosome 2 Open Reading Frame 69, COXPD53, FLJ38973, Hypothetical Protein FLJ38973, Mitochondrial protein C2orf69

---

Product Information

32100-1-PBS targets C2orf69 in WB, IHC, Indirect ELISA applications and shows reactivity with mouse, rat samples.

• Tested Reactivity: mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: C2orf69 fusion protein Ag36779
• Full Name: chromosome 2 open reading frame 69
• Calculated Molecular Weight: 43 kDa
• Observed Molecular Weight: 50 kDa
• GenBank Accession Number: BC036456
• Gene Symbol: C2orf69
• Gene ID (NCBI): 205327
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• UNIPROT ID: Q8N8R5
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Chromosome 2 open reading frame 69 (C2orf69, also known as COXPD53) is located in the mitochondrion. It can affect mitochondrial membrane potential and oxidative respiration in cultured neurons and controls the levels of the glycogen branching enzyme 1 (GBE1) (PMID: 34038740; 33945503). The variant in C2orf69 probably causes developmental regression, seizures, microcephaly, autistic features, and hypertonia (PMID: 37337918). Its deficiency can disrupt the development and homeostasis of the immune and central nervous systems (PMID: 34038740).