Product Information
60173-3-PBS targets CD1A in WB, Indirect ELISA applications and shows reactivity with Human, Pig samples.
Tested Reactivity | Human, Pig |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen |
CatNo: Ag11304 Product name: Recombinant human CD1A protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-284 aa of BC031645 Sequence: MWNWLKEPLSFHVIWIASFYNHSWKQNLVSGWLSDLQTHTWDSNSSTIVFLWPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGCELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHENDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWEHHSSV Predict reactive species |
Full Name | CD1a molecule |
Calculated Molecular Weight | 327 aa, 37 kDa |
Observed Molecular Weight | 50-55 kDa |
GenBank Accession Number | BC031645 |
Gene Symbol | CD1A |
Gene ID (NCBI) | 909 |
RRID | AB_2881353 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | P06126 |
Storage Buffer | PBS only, pH 7.3. |
Storage Conditions | Store at -80°C. |
Background Information
CD1a is an antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. During protein synthesis and maturation, CD1 family members bind endogenous lipids that are replaced by lipid or glycolipid antigens when the proteins are internalized and pass through endosomes, before trafficking back to the cell surface.