CoraLite® Plus 647 Anti-Mouse CD324 (E-cadherin) (DECMA-1)

CD324 (E-cadherin) Monoclonal Antibody for FC

Host / Isotype

Rat / IgG1, kappa


Mouse, Human, Canine and More (1)




CoraLite® Plus 647 Fluorescent Dye



Cat no : CL647-65241


AA960649, cadherin 1, Cdh1, Ecad, L CAM, Um, UVO

Tested Applications

Positive FC detected inMDCK cells

Recommended dilution

This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

CL647-65241 targets CD324 (E-cadherin) in FC applications and shows reactivity with Mouse, Human, Canine samples.

Tested Reactivity Mouse, Human, Canine
Cited Reactivitymouse
Host / Isotype Rat / IgG1, kappa
Class Monoclonal
Type Antibody
Immunogen Mouse embryonal carcinoma cell line PCC4 Aza RI
Full Name cadherin 1
GenBank Accession NumberBC098501
Gene Symbol Cdh1
Gene ID (NCBI) 12550
Conjugate CoraLite® Plus 647 Fluorescent Dye
Excitation/Emission Maxima Wavelengths654 nm / 674 nm
Form Liquid
Purification MethodN/A
Storage Buffer PBS with 0.09% sodium azide.
Storage ConditionsStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Background Information

Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. E-cadherin (epithelial cadherin), also known as CDH1 (cadherin 1) or CAM 120/80, is a classical member of the cadherin superfamily which also include N-, P-, R-, and B-cadherins. It has been regarded as a marker for spermatogonial stem cells in mice(PMID:23509752). E-cadherin is expressed on the cell surface in most epithelial tissues. The extracellular region of E-cadherin establishes calcium-dependent homophilic trans binding, providing specific interaction with adjacent cells, while the cytoplasmic domain is connected to the actin cytoskeleton through the interaction with p120-, α-, β-, and γ-catenin (plakoglobin). E-cadherin is important in the maintenance of the epithelial integrity, and is involved in mechanisms regulating proliferation, differentiation, and survival of epithelial cell. E-cadherin may also play a role in tumorigenesis. It is considered to be an invasion suppressor protein and its loss is an indicator of high tumor aggressiveness.


Product Specific Protocols
FC protocol for CL Plus 647 CD324 (E-cadherin) antibody CL647-65241Download protocol
Standard Protocols
Click here to view our Standard Protocols



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