CD68-Specific Polyclonal antibody

CD68-Specific Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, IF,ELISA

Conjugate

Unconjugated

Cat no : 16192-1-AP

Synonyms

CD68, CD68 molecule, GP110, Macrosialin, SCARD1



Tested Applications

Recommended dilution

ApplicationDilution
Sample-dependent, check data in validation data gallery

Product Information

16192-1-AP targets CD68-Specific in WB, IHC, IF,ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name CD68 molecule
Calculated molecular weight 37 kDa
Observed molecular weight 100-110 kDa, 60-70 kDa
GenBank accession numberNM_001251
Gene symbol CD68
Gene ID (NCBI) 968
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

CD68 is a type I transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It belongs to the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family and primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. CD68 is also a member of the scavenger receptor family. It may play a role in phagocytic activities of tissue macrophages. This antibody is raised against a synthetic peptide (FPYGHLSFGFMQDLC) of human CD68.

Publications

SpeciesApplicationTitle
humanIHC

J Am Heart Assoc

Increased Atherosclerotic Lesions in LDL Receptor Deficient Mice With Hematopoietic Nuclear Receptor Rev-erbα Knock- Down.

Authors - Ma Hongling H
mouseWB

PLoS One

Loss of Metabotropic Glutamate Receptor 5 Function on Peripheral Benzodiazepine Receptor in Mice Prenatally Exposed to LPS.

Authors - Dany Arsenault
humanIF

J Vis Exp

Development and Identification of a Novel Subpopulation of Human Neutrophil-derived Giant Phagocytes In Vitro.

Authors - Lena Lavie