|Sample-dependent, check data in validation data gallery|
16192-1-AP targets CD68-Specific in WB, IHC, IF,ELISA applications and shows reactivity with human, mouse samples.
|Tested Reactivity||human, mouse|
|Cited Reactivity||human, mouse|
|Host / Isotype||Rabbit / IgG|
|Full Name||CD68 molecule|
|Calculated molecular weight||37 kDa|
|Observed molecular weight||100-110 kDa, 60-70 kDa|
|GenBank accession number||NM_001251|
|Gene ID (NCBI)||968|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
CD68 is a type I transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It belongs to the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family and primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. CD68 is also a member of the scavenger receptor family. It may play a role in phagocytic activities of tissue macrophages. This antibody is raised against a synthetic peptide (FPYGHLSFGFMQDLC) of human CD68.
J Am Heart Assoc
Increased Atherosclerotic Lesions in LDL Receptor Deficient Mice With Hematopoietic Nuclear Receptor Rev-erbα Knock- Down.
Loss of Metabotropic Glutamate Receptor 5 Function on Peripheral Benzodiazepine Receptor in Mice Prenatally Exposed to LPS.
J Vis Exp
Development and Identification of a Novel Subpopulation of Human Neutrophil-derived Giant Phagocytes In Vitro.