|Positive WB detected in||A431 cells|
|Positive IP detected in||A431 cells|
|Positive IHC detected in||human breast cancer tissue, human stomach cancer tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Positive IF detected in||A431 cells|
|Positive FC detected in||A431 cells|
|Western Blot (WB)||WB : 1:500-1:2000|
|Immunoprecipitation (IP)||IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB|
|Immunohistochemistry (IHC)||IHC : 1:50-1:500|
|Immunofluorescence (IF)||IF : 1:50-1:500|
|Sample-dependent, check data in validation data gallery|
13773-1-AP targets P-cadherin in WB, IP, IHC, IF, FC, ELISA applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||human, mouse, rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||P-cadherin fusion protein Ag4758|
|Full Name||cadherin 3, type 1, P-cadherin (placental)|
|Calculated molecular weight||829 aa, 91 kDa|
|Observed molecular weight||120 kDa|
|GenBank accession number||BC041846|
|Gene ID (NCBI)||1001|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. P-cadherin (placental cadherin), also known as CDH3 (cadherin 3), is a classical member of the cadherin superfamily which also include E-, N-, R-, and B-cadherins. Aberrant expression of P-cadherin has been reported in many cancers, including breast, gastric, endometrial, ovarian, and prostate cancer.
|Product Specific Protocols|
|WB protocol for P-cadherin antibody 13773-1-AP||Download protocol|
|IHC protocol for P-cadherin antibody 13773-1-AP||Download protocol|
|IF protocol for P-cadherin antibody 13773-1-AP||Download protocol|
|IP protocol for P-cadherin antibody 13773-1-AP||Download protocol|
|FC protocol for P-cadherin antibody 13773-1-AP||Download protocol|
|Click here to view our Standard Protocols|
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