P-cadherin Polyclonal antibody
P-cadherin Polyclonal Antibody for FC, IF, IHC, IP, WB,ELISA
Host / Isotype
Rabbit / IgG
human, mouse, rat
WB, IP, IHC, IF, FC, ELISA
Cat no : 13773-1-AP
Validation Data Gallery
|Positive WB detected in||A431 cells|
|Positive IP detected in||A431 cells|
|Positive IHC detected in||human breast cancer tissue, human stomach cancer tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Positive IF detected in||A431 cells|
|Positive FC detected in||A431 cells|
|Western Blot (WB)||WB : 1:500-1:2000|
|Immunoprecipitation (IP)||IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB|
|Immunohistochemistry (IHC)||IHC : 1:50-1:500|
|Immunofluorescence (IF)||IF : 1:50-1:500|
|Sample-dependent, check data in validation data gallery|
|WB||See 5 publications below|
|IHC||See 3 publications below|
|IF||See 2 publications below|
13773-1-AP targets P-cadherin in WB, IP, IHC, IF, FC, ELISA applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||human, mouse, rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||P-cadherin fusion protein Ag4758|
|Full Name||cadherin 3, type 1, P-cadherin (placental)|
|Calculated molecular weight||829 aa, 91 kDa|
|Observed molecular weight||120 kDa|
|GenBank accession number||BC041846|
|Gene ID (NCBI)||1001|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. P-cadherin (placental cadherin), also known as CDH3 (cadherin 3), is a classical member of the cadherin superfamily which also include E-, N-, R-, and B-cadherins. Aberrant expression of P-cadherin has been reported in many cancers, including breast, gastric, endometrial, ovarian, and prostate cancer.
|Product Specific Protocols|
|WB protocol for P-cadherin antibody 13773-1-AP||Download protocol|
|IHC protocol for P-cadherin antibody 13773-1-AP||Download protocol|
|IF protocol for P-cadherin antibody 13773-1-AP||Download protocol|
|IP protocol for P-cadherin antibody 13773-1-AP||Download protocol|
|FC protocol for P-cadherin antibody 13773-1-AP||Download protocol|
|Click here to view our Standard Protocols|
Symmetry breaking of tissue mechanics in wound induced hair follicle regeneration of laboratory and spiny mice.
Mol Ther Nucleic Acids
Inhibition of the lncRNA MIAT prevents podocyte injury and mitotic catastrophe in diabetic nephropathy.
Screening and Identification of Key Biomarkers of Gastric Cancer: Three Genes Jointly Predict Gastric Cancer.
Int J Biol Sci
KLF4-Mediated CDH3 Upregulation Suppresses Human Hepatoma Cell Growth and Migration via GSK-3β Signaling.
Aging (Albany NY)
Transcriptional dysregulation of TRIM29 promotes colorectal cancer carcinogenesis via pyruvate kinase-mediated glucose metabolism.
BMC Complement Med Ther
Vincetoxicum arnottianum modulates motility features and metastatic marker expression in pediatric rhabdomyosarcoma by stabilizing the actin cytoskeleton.