p35 Polyclonal antibody

p35 Polyclonal Antibody for IP, WB,ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat





Cat no : 18346-1-AP


CDK5 activator 1, CDK5P35, CDK5R, CDK5R1, NCK5A, p23, p25, p35, p35nck5a, TPKII regulatory subunit

Tested Applications

Positive WB detected inmouse brain tissue
Positive IP detected inmouse brain tissue

Recommended dilution

Western Blot (WB)WB : 1:500-1:1000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
Sample-dependent, check data in validation data gallery

Published Applications

WBSee 1 publications below

Product Information

The immunogen of 18346-1-AP is p35 Fusion Protein expressed in E. coli.

Tested Reactivity human, mouse, rat
Cited Reactivitymouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen p35 fusion protein Ag13152
Full Name cyclin-dependent kinase 5, regulatory subunit 1 (p35)
Calculated molecular weight 34 kDa
Observed molecular weight 34 kDa
GenBank accession numberBC020580
Gene symbol CDK5R1
Gene ID (NCBI) 8851
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Cyclin dependent kinase-5 (Cdk5), is an atypical but essential member of the Cdk family of proline-directed serine/threonine kinases. CDK5R1 encodes p35, a specific activator of the serine/threonine kinase CDK5, which plays a central role in neuronal migration and differentiation during central nervous system development. The p35 form of this protein is proteolytically cleaved by calpain, generating a p25 form.


Product Specific Protocols
WB protocol for p35 antibody 18346-1-APDownload protocol
IP protocol for p35 antibody 18346-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols




Inhibition of Cdk5 rejuvenates inhibitory circuits and restores experience-dependent plasticity in adult visual cortex.

Authors - Yue Li