CEA Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 10421-1-AP

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Freight/Packing

Con: 30 μg/150 μl

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Species specificity:
human

Positive IHC detected in:
human colon cancer tissue, human colon tissue, human colon cancer tissue, human lung cancer tissue, human pancreas cancer tissue, human stomach cancer tissue

Recommended dilution:
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
carcinoembryonic antigen-related cell adhesion molecule 5

Calculated molecular weight:
77 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CEACAM5

Synonyms
Carcinoembryonic antigen, CD66e, CEA, CEACAM5, DKFZp781M2392, Meconium antigen 100
Background

Carcinoembryonic antigen (CEA), also known as CEACAM5 or CD66e, is a cell surface glycoprotein belonging to the immunoglobulin superfamily, mainly serving as a cell adhesion molecule mediating intercellular contact by both homophilic and heterophilic binding (PMID: 21731662). CEA inhibits anoikis and plays a role in tumorigenesis and metastasis. CEA has been found to be overexpressed in a wide variety of human cancers, including colon, breast, and lung (PMID: 17167768). CEA is a tumor marker and is routinely exploited for diagnosis.


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