CEACAM1/CD66a Polyclonal antibody, PBS Only

• 

  IHC staining of human colon using 30347-1-AP (same clone as 30347-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 30347-1-AP (CEACAM1/CD66a antibody) at dilution of 1:2000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30347-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human colon using 30347-1-AP (same clone as 30347-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 30347-1-AP (CEACAM1/CD66a antibody) at dilution of 1:2000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30347-1-PBS in a different storage buffer formulation.

CEACAM1/CD66a Polyclonal Antibody for IHC, Indirect ELISA

Cat No. 30347-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, Indirect ELISA

Synonyms

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Product Information

30347-1-PBS targets CEACAM1/CD66a in IHC, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  Recombinant protein

• Full Name: carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
• Calculated Molecular Weight: 526 aa, 58 kDa
• GenBank Accession Number: BC014473
• Gene Symbol: CEACAM1
• Gene ID (NCBI): 634
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: P13688
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

CEACAM1, also known as CD66a or BGP (biliary glycoprotein), is a member of the cacinoembryonic antigen (CEA) family which belongs to the immunoglobulin superfamily of cell adhesion molecules (PMID: 16919437). CEACAMs play major roles in cell-cell and cell-ECM adhesion and have been implicated in the control of cell proliferation, angiogenesis, and tissue remodeling (PMID: 23021083). CEACAM1 is a transmembrane glycoprotein that is expressed on epithelial, endothelial, and immune cells (PMID: 30314283). CEACAM1 has been demonstrated to play a role in morphogenesis, apoptosis, angiogenesis, cell proliferation, cell motility, fibrosis, and immunity (PMID: 31604530).