CFHR3 Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 16583-1-AP

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Freight/Packing

Con: 42 μg/150 μl

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Species specificity:
human

Positive WB detected in:
human heart tissue

Positive IP detected in:
HepG2 cells

Positive IHC detected in:
human liver tissue

Recommended dilution:
WB : 1:500-1:3000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
complement factor H-related 3

Calculated molecular weight:
330aa,37 kDa

Observed molecular weight:
45-56 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CFHR3

Synonyms
CFHL3, CFHR3, complement factor H related 3, DOWN16, FHR 3, FHR3, H factor like protein 3, HLF4
Background

CFHR3, also named as DOWN16, belongs to the complement factor H-related protein family. Expressed by the liver and secreted in plasma, human CFHR3 is composed of five short consensus repeats (SCRs), and it also has a 19-amino acid signal peptide and four N-linked glycosylation sites. It may be involved in complement regualtion. A frequent deletion of CFHR1 and CFHR3 genes was found to be associated with decrease risk of aged-related macular degeneration (AMD), and with an increased risk of atypical hemolytic-uremic syndrome (aHUS).


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