Chromogranin A Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 10529-1-AP

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Freight/Packing

Con: 37 μg/150 μl

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Species specificity:
human, mouse

Positive IHC detected in:
human pancreas tissue,human lung cancer tissue, human colon tissue

Recommended dilution:
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
chromogranin A (parathyroid secretory protein 1)

Calculated molecular weight:
51 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CHGA

Synonyms
CGA, CHGA, Chromogranin A, Pituitary secretory protein I, SP I, Vasostatin I Vasostatin 2
Background

Chromogranin A is a member of the granin family of neuroendocrine secretory proteins. It is located in secretory vesicles of neurons and endocrine cells. Chromogranin A is the precursor to several functional peptides including vasostatin, pancreastatin, catestatin and parastatin. These peptides negatively modulate the neuroendocrine function of the releasing cell (autocrine) or nearby cells (paracrine). CgA is one of the most used tumor markers in NET's (neuroendocrine tumors) , and elevated CgA concentrations have been demonstrated in serum or plasma of patients with different types of these tumors.


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