Calsyntenin-1 Polyclonal antibody

Calsyntenin-1 Polyclonal Antibody for WB, IP, IHC, ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat





Cat no : 12788-1-AP


ALC ALPHA, Alcadein alpha, alcalpha1, alcalpha2, C terminal fragment 1 alpha, calsyntenin 1, Calsyntenin-1, CLSTN1, CS1, CSTN1, KIAA0911, PIK3CD, SAlc alpha CTF1 alpha, XB31alpha

Tested Applications

Positive WB detected inhuman brain tissue
Positive IP detected inmouse brain tissue
Positive IHC detected inmouse brain tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

Western Blot (WB)WB : 1:500-1:2400
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

12788-1-AP targets Calsyntenin-1 in WB, IP, IF, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Calsyntenin-1 fusion protein Ag3504
Full Name calsyntenin 1
Calculated Molecular Weight 109 kDa
Observed Molecular Weight 109-130 kDa
GenBank Accession NumberBC033902
Gene Symbol CLSTN1
Gene ID (NCBI) 22883
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Calsyntenins (calsyntenin-1, -2, -3) compose a family of neuronally expressed proteins that belong to the cadherin superfamily of cell adhesion molecules (PMID: 24966372; 12498782). Calsyntenin-1 (CLSTN1) is a proteolytically processed postsynaptic membrane protein with a cytoplasmic calcium-binding domain. By binding Ca2+, calsyntenin-1 may modulate Ca2+-mediated postsynaptic signals (PMID: 11161476). Calsyntenin-1 is a transmembrane cargo-docking protein for Kinesin-1-mediated vesicular transport (PMID: 16760430). It can mediate axonal transport of the amyloid precursor protein and regulate Aβ production (PMID: 22434822).


Product Specific Protocols
WB protocol for Calsyntenin-1 antibody 12788-1-APDownload protocol
IHC protocol for Calsyntenin-1 antibody 12788-1-APDownload protocol
IP protocol for Calsyntenin-1 antibody 12788-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



J Neurosci

The cleavage products of amyloid-beta precursor protein are sorted to distinct carrier vesicles that are independently transported within neurites.

Authors - Muresan Virgil V

Front Oncol

Long Non-coding RNA AK025387 Promotes Cell Migration and Invasion of Gastric Cancer.

Authors - Yi-Yuan Sun

Cardiovasc Drugs Ther

Calsyntenin-1 Promotes Doxorubicin-induced Dilated Cardiomyopathy in Rats

Authors - Mingxiang Zhu

Cell Rep

A program of successive gene expression in mouse one-cell embryos

Authors - Maki Asami

Cell Death Discov

ESRP1-driven alternative splicing of CLSTN1 inhibits the metastasis of gastric cancer

Authors - Chengguo Li

J Cancer Res Clin Oncol

Explore the alterations of downstream molecular pathways caused by ARID1A mutation/knockout in human endometrial cancer cells

Authors - Baoling Xing


The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


Boyan (Verified Customer) (12-09-2019)

This antibody gave a clean band around 100 kD, like that is shown in its datasheet. However, in literature, people showed that this protein runs as doublet bands at 130 - 150 kD due to its glycosylation. Therefore, this antibody is highly suspicious for recognizing another protein rather than Clstn1 itself.

  • Applications: Western Blot,