This product is currently not available for sale.


Product Information

30986-1-PBS targets CLUH in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, monkey samples.

Tested Reactivity human, mouse, monkey
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen CLUH fusion protein Ag34275 Predict reactive species
Full Name KIAA0664
Observed Molecular Weight147-150 kDa
GenBank Accession NumberBC156940
Gene Symbol CLUH
Gene ID (NCBI) 23277
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity Purification
UNIPROT IDO75153
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

Clustered mitochondria homolog (CLUH) is a conserved RNA-binding protein, that binds transcripts encoding proteins involved in the respiratory chain, the tricarboxylic acid (TCA) cycle, and other mitochondrial metabolic pathways. Upon loss of CLUH, target mRNAs are subjected to faster decay, and their respective proteins are decreased in abundance. This leads to alterations in mitochondrial distribution (mitochondrial clustering as the gene name alludes to) mitochondrial cristae integrity, respiratory defects, loss of mtDNA, and decreased activity of TCA cycle enzymes. (PMID: 35559794)

Loading...