Casein Kinase 2 beta Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 22418-1-AP

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Freight/Packing

Con: 48 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
MCF-7 cells, HeLa cells, HepG2 cells, NIH/3T3 cells

Positive IHC detected in:
human testis tissue, human breast cancer tissue, human thyroid tissue, mouse testis tissue

Positive IF detected in:
HeLa cells

Positive FC detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:50-1:500
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
casein kinase 2, beta polypeptide

Calculated molecular weight:
215aa,25 kDa

Observed molecular weight:
25-30 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CSNK2B

Synonyms
Casein kinase II subunit beta, CK II beta, CK2B, CK2N, CSK2B, CSNK2B, G5A, Phosvitin, Protein G5a
Background

Casein kinase II subunit beta is a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. It participates in Wnt signaling, and plays a complex role in regulating the basal catalytic activity of the alpha subunit.


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