|Positive WB detected in||MCF-7 cells, MDA-MB-453s cells|
|Western Blot (WB)||WB : 1:500-1:1000|
|Sample-dependent, check data in validation data gallery|
The immunogen of 23840-1-AP is Cathepsin G Fusion Protein expressed in E. coli.
|Host / Isotype||Rabbit / IgG|
|Immunogen||Cathepsin G fusion protein Ag20818|
|Full Name||cathepsin G|
|Calculated molecular weight||29 kDa|
|Observed molecular weight||29 kDa, 35 kDa|
|GenBank accession number||BC014460|
|Gene ID (NCBI)||1511|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
CTSG(Cathepsin G) is also named as CTLA, CG, MGC23078, Catg and belongs to the peptidase S1 family. It may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. CTSG may also play a role in the progression to heart failure by activating angiotensin II, leading to detrimental effects on the heart. The full length protein contains 255 amino acid and has a signal peptide, a propeptide and a glycosylation site.
Stable depletion of RUNX1-ETO in Kasumi-1 cells induces expression and enhanced proteolytic activity of Cathepsin G and Neutrophil Elastase.
Cathepsin C promotes breast cancer lung metastasis by modulating neutrophil infiltration and neutrophil extracellular trap formation.