CX3CR1 Monoclonal antibody
CX3CR1 Monoclonal Antibody for WB,ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human
Applications
WB,ELISA
Conjugate
Unconjugated
CloneNo.
3D3B8
Cat no : 66915-1-Ig
Synonyms
Validation Data Gallery
Tested Applications
Positive WB detected in | HEK-293 cells, Jurkat cells, SH-SY5Y cells, U-937 cells |
Recommended dilution
Application | Dilution |
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Western Blot (WB) | WB : 1:2000-1:10000 |
Sample-dependent, check data in validation data gallery |
Product Information
66915-1-Ig targets CX3CR1 in WB,ELISA applications and shows reactivity with Human samples.
Tested Reactivity | Human |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | CX3CR1 fusion protein Ag27698 |
Full Name | chemokine (C-X3-C motif) receptor 1 |
Calculated molecular weight | 40 kDa |
Observed molecular weight | 44 kDa |
GenBank accession number | BC028078 |
Gene symbol | CX3CR1 |
Gene ID (NCBI) | 1524 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
CX3CR1, also known as GPR13, V28 and fractalkine receptor, belongs to the 7-transmembrane G protein-coupled receptor (GPCR) family. It is expressed on microglia, astrocytes, NK cells, monocytes/macrophages, and a subpopulation of T cells. CX3CR1 is the receptor for fractalkine (CX3CL1) and mediates both its adhesive and migratory functions. It also acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro), and some variations in the gene of CX3CR1 lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Defects in CX3CR1 are a cause of susceptibility to age-related macular degeneration type 12 (ARMD12).
Protocols
Product Specific Protocols | |
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WB protocol for CX3CR1 antibody 66915-1-Ig | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |