CXCR7 Monoclonal antibody

CXCR7 Monoclonal Antibody for IF, IHC, WB, ELISA

Host / Isotype

Mouse / IgG2b


human, mouse







Cat no : 60216-1-Ig


ACKR3, Chemokine orphan receptor 1, CMKOR1, CXC R7, CXCR 7, CXCR7, G protein coupled receptor 159, GPR159, RDC 1, RDC1

Tested Applications

Positive WB detected inPC-3 cells, U-87 MG cells, Jurkat cells, Raji cells, K-562 cells, THP-1 cells
Positive IHC detected inhuman breast cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inhuman breast cancer tissue, human prostate cancer tissue

Recommended dilution

Western Blot (WB)WB : 1:1000-1:6000
Immunohistochemistry (IHC)IHC : 1:20-1:200
Immunofluorescence (IF)IF : 1:200-1:800
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Published Applications

IHCSee 1 publications below

Product Information

60216-1-Ig targets CXCR7 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivityhuman
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Immunogen CXCR7 fusion protein Ag14247
Full Name chemokine (C-X-C motif) receptor 7
Calculated Molecular Weight 362 aa, 41 kDa
Observed Molecular Weight 50-60 kDa
GenBank Accession NumberBC036661
Gene Symbol CXCR7
Gene ID (NCBI) 57007
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

CXCR7 (C-X-C chemokine receptor type 7), also known as RDC1, is a member of the G-protein coupled receptor family. CXCR7 can bind the chemokines CXCL11 and CXCL12 with high affinity, and it also acts as a coreceptor with CXCR4 for a restricted number of HIV isolates. Expression of CXCR7 has been associated with cardiac development as well as with tumor growth and progression. This antibody recognizes endogenous CXCR7, which has an experimentally determined molecular weight of 50 kDa (PMID: 20197403; 20388803).


Product Specific Protocols
WB protocol for CXCR7 antibody 60216-1-IgDownload protocol
IHC protocol for CXCR7 antibody 60216-1-IgDownload protocol
IF protocol for CXCR7 antibody 60216-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Urol Oncol

The inflammation-related biomarker CXCR7 independently predicts patient outcome after radical prostatectomy.

Authors - Pedro Bargão Santos