CXorf57 Polyclonal antibody

• 

  WB analysis using 25960-1-AP

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 25960-1-AP (CXorf57 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

CXorf57 Polyclonal Antibody for WB, ELISA

Cat No. 25960-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

Synonyms

RADX

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Tested Applications

• Positive WB detected in: mouse brain tissue

Recommended dilution

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

25960-1-AP targets CXorf57 in WB, ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag22707

  Product name: Recombinant human CXorf57 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 1-355 aa of BC070110

  Sequence: MSGESGQPEAGPSHAGLDWPNPERNRAGVPGGLIRRAGSQGPRSWIQKVLEQIMDSPRQCVTPSEVVPVTVLAVQRYLLEDEPRDTVPKPPLYCYDVTISDGVYQEKCYLDPSLNSLVYQNILKVGIQMRISRVSCLYNEKRIGQGILCIDNVHCGETSDSISLETPFRNRAHQEKPERPLRGGKSHYLALWNNEDPYGDIWLTDKQPEEHNFSDTKIISLSHLEMTWTNRRNFPALLVRILHKSKLRYYGKPDKKMIEPYQTFLEVADSSGTVSVIMWNALCPEWYKSLRVGLVLLLQDYSVKKSYPFRIQPVPVDPQIKLISTMEICLNLRDPPTNIIIIPEKQVKPEWRLPK

• Full Name: chromosome X open reading frame 57
• Calculated Molecular Weight: 855 aa, 98 kDa
• Observed Molecular Weight: 97 kDa
• GenBank Accession Number: BC070110
• Gene Symbol: CXorf57
• Gene ID (NCBI): 55086
• RRID: AB_3669513
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q6NSI4
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

CXorf57, also known as RADX, is a previously unrecognized OB fold domain-containing factor that interacts with ssDNA regions at DNA replication sites. CXorf57 contains three potential N-terminal OB folds, a domain organization similar to that of the RPA1 subunit within the RPA complex. It plays an important role in supporting replication fork stability during normal S phase and in response to replication stress (PMID: 29021206).