|Positive WB detected in||human placenta tissue, mouse lung tissue|
|Western Blot (WB)||WB : 1:500-1:1000|
|Sample-dependent, check data in validation data gallery|
20230-1-AP targets DLL1-Specific in WB, ELISA applications and shows reactivity with human, mouse samples.
|Tested Reactivity||human, mouse|
|Cited Reactivity||human, mouse|
|Host / Isotype||Rabbit / IgG|
|Full Name||delta-like 1 (Drosophila)|
|Calculated molecular weight||723 aa, 78 kDa|
|Observed molecular weight||80 kDa|
|GenBank accession number||NM_005618|
|Gene ID (NCBI)||28514|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
DLL1, also named as Delta1, acts as a ligand for Notch receptors. DLL1 blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor. The antibody is specific to the protein DLL1.
Transcriptional control of brain tumor stem cells by a carbohydrate binding protein
J Transl Med
MicroRNA-143 acts as a tumor suppressor through Musashi-2/DLL1/Notch1 and Musashi-2/Snail1/MMPs axes in acute myeloid leukemia
Int J Cancer
Modification of α2,6-sialylation mediates the invasiveness and tumorigenicity of non-small cell lung cancer cells in vitro and in vivo via Notch1/Hes1/MMPs pathway.
MiR-34a-5p promotes multi-chemoresistance of osteosarcoma through down-regulation of the DLL1 gene.
Cell Death Dis
hPER3 promotes adipogenesis via hHSP90AA1-mediated inhibition of Notch1 pathway.