Drebrin Recombinant antibody, PBS Only

Drebrin Uni-rAbTM Recombinant Antibody for WB, IHC, FC (Intra), Cytometric bead array, Indirect ELISA

Cat No. 83591-2-PBS
Clone No.240599G12

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, FC (Intra), Cytometric bead array, Indirect ELISA

DBN1, 240599G12, DBN 1, Developmentally-regulated brain protein, drebrin 1

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

83591-2-PBS targets Drebrin in WB, IHC, FC (Intra), Cytometric bead array, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Drebrin fusion protein Ag0371 Predict reactive species
Full Name drebrin 1
Calculated Molecular Weight 71 kDa
Observed Molecular Weight 110-130 kDa
GenBank Accession NumberBC000283
Gene Symbol Drebrin
Gene ID (NCBI) 1627
ENSEMBL Gene IDENSG00000113758
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ16643
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

Drebrin (DBN1) is an actin binding and stabilizing protein with roles in endocytosis, formation of dendrite spines in neurons and coordinating cell-cell synapses in immune cells. Preferentially expressed in the brain, it is highly localized in dendritic spines and regulates spine shapes. It has two isoforms that are splice variants, with drebrin A being expressed in neural cells, and drebrin E is present in several other cell types. Recently it has been reported that circulating DBN1 levels correlated with retinal nerve fiber layer defect and may reflect the severity of retinal ganglion cells injury in glaucoma patients.

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