ERK1/2 Antibody 51 Publications

Rabbit Polyclonal| Catalog number: 16443-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 30 μg/150 μl

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Species specificity:
human, mouse, rat, zebrafish, A. sphaerocephala Krasch, pig, sheep

Positive WB detected in:
HeLa cells,HepG2/A431 cells , mouse brain tissue, rat brain tissue, NIH/3T3 cells, mouse kidney tissue, PC-3 cells, A431 cells, HEK-293 cells, rat kidney tissue

Positive IHC detected in:
human liver tissue, human kidney tissue, human liver tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:1000-1:4000
IHC : 1:50-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
mitogen-activated protein kinase 1

Calculated molecular weight:
360aa,41 kDa

Observed molecular weight:
38-44 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
MAPK1

Synonyms
ERK, ERK 2, ERK1/2, ERK2, ERT1, MAP kinase 1, MAP kinase 2, MAP kinase isoform p42, MAPK 1, MAPK 2, MAPK1, MAPK2, p40, p41, p41mapk, p42 MAPK, P42MAPK, PRKM1, PRKM2
Background

ERK1 and ERK2 belongs to the protein kinase superfamily. It is involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. ERK1/2 catalized the reaction: ATP + a protein = ADP + a phosphoprotein. It is activated by tyrosine phosphorylation in response to insulin and NGF. This antibody can recognize both ERK1 and ERK2 with the molecular mass of 38-43 kDa.


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