FAM107A Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 12176-1-AP

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Freight/Packing

Con: 26 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
Transfected HEK-293 cells

Positive IHC detected in:
human lung cancer tissue

Positive IF detected in:
MCF-7 cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:50-1:500
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
family with sequence similarity 107, member A

Calculated molecular weight:
144aa,17 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
FAM107A

Synonyms
DRR1, FAM107A, FLJ30158, FLJ45473, Protein FAM107A, Protein TU3A, TU3A
Background

FAM107A, also named as TU3A, encodes a 144 amino-acid protein, which contains a coiled-coil domain and a nuclear localization signal. FAM107A as a transcription factor regulates some gene transcription and signal transduction in cell. With the exception of peripheral blood cells, FAM107A is widely expressed in normal tissues, but shows significant loss of expression in renal cell carcinomas and frequent loss of expression in cervical, gastric, ovarian and non small cell lung cancers. Transfection of FAM107A mRNA into cancer cell line inhibits cell growth and proliferation, supporting the evidence that the gene functions as an important tumor suppressor.


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