|Positive WB detected in||HepG2 cells, mouse lung tissue|
|Positive IHC detected in||human breast cancer tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Positive IF detected in||HepG2 cells|
|Western Blot (WB)||WB : 1:200-1:1000|
|Immunohistochemistry (IHC)||IHC : 1:50-1:500|
|Immunofluorescence (IF)||IF : 1:50-1:500|
|Sample-dependent, check data in validation data gallery|
11098-1-AP targets FGFR4 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||human, mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||FGFR4 fusion protein Ag1573|
|Full Name||fibroblast growth factor receptor 4|
|Calculated molecular weight||88 kDa|
|Observed molecular weight||100-110 kDa|
|GenBank accession number||BC011847|
|Gene ID (NCBI)||2264|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
FGF1 Signaling Modulates Biliary Injury and Liver Fibrosis in the Mdr2-/- Mouse Model of Primary Sclerosing Cholangitis.
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FGFR4 Gly388Arg Polymorphism Affects the Progression of Gastric Cancer by Activating STAT3 Pathway to Induce Epithelial to Mesenchymal Transition.
Int J Oncol
Role of fibroblast growth factor 4 in the growth and metastasis of colorectal cancer.
J Cell Biochem
Glycosylation of FGFR4 in cholangiocarcinoma regulates receptor processing and cancer signaling.
Bupleuri radix extract ameliorates impaired lipid metabolism in high-fat diet-induced obese mice via gut microbia-mediated regulation of FGF21 signaling pathway.
Association between the perturbation of bile acid homeostasis and valproic acid-induced hepatotoxicity.