FUCA1 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 16420-1-AP

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Freight/Packing

Con: 22 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse liver tissue

Positive IHC detected in:
human liver tissue, human heart tissue, human kidney tissue, human liver tissue, human liver cancer tissue, human placenta tissue, human testis tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
fucosidase, alpha-L- 1, tissue

Calculated molecular weight:
461aa,53 kDa

Observed molecular weight:
54 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
FUCA1

Synonyms
Alpha L fucosidase 1, Alpha L fucosidase I, FUCA, FUCA1, fucosidase, alpha L 1, tissue, Tissue alpha L fucosidase
Background

FUCA1(a-l-Fucosidase) is a lysosomal glycosidase which is ubiquitous in eukaryotic cells. This enzyme is usually found as a soluble component of the lysosome and functions as an acid hydrolase in the degradation of numerous and diverse fucoglycoconjugates.The mammalian a-l-fucosidases are relatively large, multisubunit glycoproteins which exist in multiple molecular isoforms.This enzyme may have a role in sperm-egg interactions in the reproductive tract of the female rat. There is a precursor 54 kDa form of rat sperm fucosidase which is processed to a mature 52 kDa form of the enzyme(PMID:8836125). This protein from rat epididymis is a tetramer of 210-220 kDa, made up by two pairs of subunits of 47 and 60 kDa, and the one from human seminal plasma exists in different oligomeric forms, that is, as a dimer, as a tetramer, and as a hexamer made up of a single subunit of 56-57 kDa(PMID:16736526).


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