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  • Western Blot (WB) analysis of various lysates using GDF1 Polyclonal antibody (28345-1-AP)

    WB analysis using 28345-1-AP (same clone as 28345-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 28345-1-AP (GDF1 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28345-1-PBS in a different storage buffer formulation.

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Product Information

28345-1-PBS targets GDF1 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen GDF1 fusion protein Ag28831 Predict reactive species
Full Name growth differentiation factor 1
Calculated Molecular Weight 39 kDa
Observed Molecular Weight39 kDa
GenBank Accession NumberNM_001492
Gene Symbol GDF1
Gene ID (NCBI) 2657
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP27539
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

GDF1 is a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. Studies in rodents suggest that this protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis.