GNAQ Polyclonal antibody
GNAQ Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Cat no : 27264-1-AP
|Positive WB detected in
|PC-12 cells, HepG2 cells, mouse brain tissue
|Western Blot (WB)
|WB : 1:1000-1:3000
|It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
|Sample-dependent, check data in validation data gallery
The immunogen of 27264-1-AP is GNAQ Fusion Protein expressed in E. coli.
|Host / Isotype
|Rabbit / IgG
|GNAQ fusion protein Ag26170
|guanine nucleotide binding protein (G protein), q polypeptide
|Calculated molecular weight
|Observed molecular weight
|GenBank accession number
|Gene ID (NCBI)
|Antigen affinity purification
|PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
|Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.
GNAQ is a proto-oncogene closely related to the α subunit of guanine nucleotide-binding proteins (G proteins) that serve as key intermediates between membrane-bound G-protein-coupled receptors (GPCRs) and GPCR signalling nodes. Aberrant expression and activity of G proteins and GPCRs are frequently associated with tumorigenesis. Recent studies show that oncogenic activating mutations in GNAQ are present in 80% of the melanomas. The calculated molecular weight of GNAQ is 42 kDa. This antibody can detect a band of 38-40 kDa in SDS-PAGE. (PMID: 33993733)