GRP78/BIP Antibody 57 Publications

Rabbit Polyclonal| Catalog number: 11587-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 86 μg/150 μl

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Species specificity:
human, mouse, rat, Hamster, zebrafish

Positive WB detected in:
mouse testis tissue,MCF-7 cells, TN treated Hela , mouse liver tissue, BxPC-3 cells, HeLa cells, rat liver tissue

Positive IP detected in:
MCF-7 cells

Positive IHC detected in:
human pancreas cancer tissue, human brain tissue, human breast cancer tissue, human colon cancer tissue, human pancreas cancer tissue, mouse heart tissue

Positive IF detected in:
HepG2 cells

Positive FC detected in:
HeLa cells

Recommended dilution:
WB : 1:1000-1:6000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)

Calculated molecular weight:
78 kDa

Observed molecular weight:
70-78 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
HSPA5

Synonyms
BIP, GRP 78, GRP78, HSP A5, HSPA5, MIF2
Background

GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER).It is a constitutively expressed resident protein of the ER in all eukaryotic cells. Recently it has been reported that GRP78 is associated with apoptosis or inhibition of cancer cell growth.


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